Editor-in-Chief: Alaa Abd-Elsayed, MD, PhD
Current Issue - February 2025 - Vol 9 Issue 1
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Abstract
- 2025;9;67-69 Pain Relief in Mitochondrial Disorders: Use of Spinal Cord Stimulation in a Patient With NARP Syndrome
Case Report
Augusta L. Kiepper, DO, Timothy Morgan, DO, and Christopher J. Mallard, MD.
BACKGROUND: Neuropathy, ataxia, retinitis pigmentosa (NARP) syndrome is a mitochondrial disorder of the ATPase 6 gene. There is a wide variation of symptoms, but damage to the neuronal structures can result in chronic pain.
CASE REPORT: A 31-year-old woman’s chronic back and lower extremity pain related to NARP syndrome was successfully treated with dorsal column spinal cord stimulation (SCS).
CONCLUSIONS: SCS can be used as a means of pain management in patients with genetic etiologies. This case provides an example of treating symptoms related to genetic defects with simulation improving quality of life.